Annals of Child Neurology

Review article

September 23, 2025

Beta-Ketothiolase Deficiency: A Comprehensive Review of Genetic Variants and Pathophysiology

Sohit Kashyap, Anil Kumar, Anita Choudhary, et al.

Ann Child Neurol. 2025;33(4):135-142.

Beta-ketothiolase deficiency (BKD) is a rare autosomal recessive disorder caused by mutations in the ACAT1 gene, also known as mitochondrial acetoacetyl-coenzyme A thiolase (MAT) deficiency. This enzyme defect impairs the...

Review article

September 23, 2025

The Mechanisms of Stress in Epileptogenesis

Ha Young Jo, Sang Ook Nam

Ann Child Neurol. 2025;33(4):143-151.

Epileptogenesis is a gradual, multifaceted pathological process in which the brain undergoes structural and/or functional changes that ultimately culminate in the onset of spontaneous seizures. This process is driven by...

Original article

September 23, 2025

Clinical Features according to the Frequency of Seizures in Benign Convulsions with Mild Gastroenteritis: A Single-Center Study

Seo Hee Kim, Sanghoon Lee, Young Ok Kim

Ann Child Neurol. 2025;33(4):152-160.

Purpose: Benign convulsions with mild gastroenteritis (CwG) are typically characterized by cluster seizures. Although some studies have explored the clinical characteristics of CwG in relation to seizure frequency, available data...

Original article

September 23, 2025

The Impact of Game Addiction on Cognition and Emotions in Adolescents

Yetty Ramli, Florencia Evelyn, Heni Pristiwa Oktaviani

Ann Child Neurol. 2025;33(4):161-167.

Purpose: Game addiction has emerged as a significant mental health concern among adolescents. This study assessed the severity of gaming addiction among junior and senior high school students and examined...

Original article

October 1, 2025

Intergenerational Links between Parental Sleep Disorders and Child Sleep Health and Mental Well-Being

Ahmed Masoud Ali, Hadeer Saber Mohammed, Fatma Ahmed Hamoda, et al.

Ann Child Neurol. 2025;33(4):168-178.

Purpose: Emerging evidence highlights the intergenerational transmission of sleep disturbances and their potential influence on child mental health. However, few studies have examined these associations in Arabic-speaking populations. This study...

Original article

October 1, 2025

Brain Volumetric Differences in Pediatric Epilepsy: A Focus on Genetic Etiology

Soyoung Park, Yun-Jung Lim, Kang Min Park, et al.

Ann Child Neurol. 2025;33(4):179-190.

Purpose: To investigate brain volumetric characteristics in children with epilepsy of a genetic etiology, we retrospectively analyzed magnetic resonance imaging (MRI) volumetric data from three groups: children with epilepsy of...

Beta-Ketothiolase Deficiency: A Comprehensive Review of Genetic Variants and Pathophysiology Sohit Kashyap, Anil Kumar, Anita Choudhary, et al. Ann Child Neurol. 2025;33(4):135-142. Review article September 23, 2025 Full text PubReader ePub PDF	The Mechanisms of Stress in Epileptogenesis Ha Young Jo, Sang Ook Nam Ann Child Neurol. 2025;33(4):143-151. Review article September 23, 2025 Full text PubReader ePub PDF
Clinical Features according to the Frequency of Seizures in Benign Convulsions with Mild Gastroenteritis: A Single-Center Study Seo Hee Kim, Sanghoon Lee, Young Ok Kim Ann Child Neurol. 2025;33(4):152-160. Original article September 23, 2025 Full text PubReader ePub PDF	The Impact of Game Addiction on Cognition and Emotions in Adolescents Yetty Ramli, Florencia Evelyn, Heni Pristiwa Oktaviani Ann Child Neurol. 2025;33(4):161-167. Original article September 23, 2025 Full text PubReader ePub PDF
Intergenerational Links between Parental Sleep Disorders and Child Sleep Health and Mental Well-Being Ahmed Masoud Ali, Hadeer Saber Mohammed, Fatma Ahmed Hamoda, et al. Ann Child Neurol. 2025;33(4):168-178. Original article October 1, 2025 Full text PubReader ePub PDF	Brain Volumetric Differences in Pediatric Epilepsy: A Focus on Genetic Etiology Soyoung Park, Yun-Jung Lim, Kang Min Park, et al. Ann Child Neurol. 2025;33(4):179-190. Original article October 1, 2025 Full text PubReader ePub PDF
Spinal Cord Injury without Radiographic Abnormality: A Diagnosis that Every Pediatric Neurologist Should Recognize Hye Eun Kwon Ann Child Neurol. 2025;33(4):191-194. Letter to the editor September 26, 2025 Full text PubReader ePub PDF	Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease Masquerading as Herpes Simplex Virus Encephalitis Vykuntaraju K. Gowda, Muskan Verma, Viveka Santhosh Reddy Challa Ann Child Neurol. 2025;33(4):195-197. Letter to the editor September 23, 2025 Full text PubReader ePub PDF
Expanding the Phenotype of DNM1L-Related Mitochondrial Cytopathy: A Case Series Haleigh Stafford, Naomi Kass, Mered Parnes, et al. Ann Child Neurol. 2025;33(4):198-201. Letter to the editor September 26, 2025 Full text PubReader ePub PDF Supplementary Material