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Journal of the Korean Child Neurology Society 2004;12(2):203-206.
Published online November 30, 2004.
Aseptic Meningitis Associated with Intravenous Immunoglobulin Therapy for Myasthenia Gravis : A Report of Two Cases.
Joon Sung Kim, Geun Mo Kim, Ki Won Park, Young Jong Woo
1Department of Pediatrics, Mirae Children's Hospital, Korea. drkimjs@hanmail.net
2Department of Pediatrics, Chonnam National University Medical School, Gwangju, Korea.
Abstract
Intravenous immunoglobulin (IVIG) is widely used to treat various neurologic or autoimmune disorders in childhood. Aseptic meningitis has been reported as a rare complication of IVIG therapy. We describe two girls, aged 2 and 8 years, with myasthenia gravis who suffered from aseptic meningitis after an administration of high-dose IVIG. Any other etiologic agent were identified in neither case. Both patients recovered completely within a few days and left no sequelae. To our knowledge, these are the first such reported cases in children with myasthenia gravis.
Key Words: Immunoglobulin, Meningitis, Myasthenia gravis, Child
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