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Journal of the Korean Child Neurology Society 2013;21(3):152-161.
Published online September 30, 2013.
The Diagnostic Value of Serum Monocyte Percentage in Young Infants Suspected of Meningitis.
Ji Ho Lee, Won Seop Kim, Yong Dae Kim, Ji Hyuk Lee
1Department of Pediatrics, College of Medicine, Chungbuk National University, Cheongju, Korea. jihugy@chungbuk.ac.kr
2Department of Preventive Medicine, College of Medicine, Chungbuk National University, Cheongju, Korea.
To avoid a unnecessary lumbar puncture, we tried to find a useful tool for prediction of meningitis in infants. METHODS: One hundred and twenty four patients underwent a lumbar puncture at Chungbuk National University Hospital from Jan 1, 2011 to Dec 31, 2011. We divided them into 2 groups by the evidence of meningitis, and compared laboratory findings and clinical manifestations. RESULTS: There were 30 patients for meningitis group and 94 patients for control group. Meningitis group revealed lower serum monocyte percentage (meningitis group 10.1+/-4.7%, control group 12.2+/-5.0%, P=0.049) than control group. Other laboratory findings and clinical manifestations showed no statistically significant differences between two groups. CONCLUSION: Serum monocyte percentage could help to predict meningitis in young infants, but it is not enough to replace a lumbar puncture. We therefore think that it requires a more accurate non-invasive diagnostic tool to detect meningitis.
Key Words: Meningitis, Infant, Monocyte
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