A Case of Primary Antiphospholipid Syndrome with a Cerebrovascular Attack in a Child.

Kim,  Sun Young; Lee,  In Goo; Choi,  Byung Jun; Kim,  Young Hoon; Chung,  Seung Yun; Kim,  Hack Ki; Whang,  Kyung Tai

Case Report

Journal of the Korean Child Neurology Society 2000;8(2):309-313.
Published online December 30, 2000.

A Case of Primary Antiphospholipid Syndrome with a Cerebrovascular Attack in a Child.

Sun Young Kim, In Goo Lee, Byung Jun Choi, Young Hoon Kim, Seung Yun Chung, Hack Ki Kim, Kyung Tai Whang

Department of Pediatrics, College of Medicine, Catholic University of Korea, Seoul, Korea.

Abstract

The antiphospholipid syndrome is a multisystemic disorder comprising of venous and arterial thrombotic events, recurrent unexplained fetal losses, moderate thrombocytopenia, and a high frequency of neurologic events with laboratory findings of a positive lupus anticoagulant test or anticardiolipin antibody. It may occur in association with other disorders, particularly autoimmune diseases, in which case it is referred to as secondary antiphospholipid syndrome. But when it occurs without obvious underlying disease, it is primary antiphospholipid syndrome. We report a case of primary antiphospholipid syndrome in a 5 year old female child who had a cerebrovascular attack, moderate thrombocytopenia and splenomegaly.

Key Words: Primary antiphospholipid syndrome