A Case of Acute Necrotizing Encephalopathy.

Kim,  Ja Hyung; Yun,  Hye Jin; Kim,  Deok Soo; Ko,  Tae Sung; Choi,  Choong Gon

Case Report

Journal of the Korean Child Neurology Society 2001;9(1):134-139.
Published online May 30, 2001.

A Case of Acute Necrotizing Encephalopathy.

Ja Hyung Kim, Hye Jin Yun, Deok Soo Kim, Tae Sung Ko, Choong Gon Choi

Abstract

Acute necrotizing encephalopathy is a recently established disease entity, proposed by Mizuguchi et al in 1995, that shows a characteristic symmetric and multifocal involvement of both thalamus, brainstem tegmentum, cerebral periventricular white matter, and cerebellar medulla. It is known to be prevalent in Japan and other Far Ease countries. The etiology of the acute necrotizing encephalopathy remains unknown. The typical course of acute necrotizing encephalopathy is the development of the irreversible neurologic symptoms related to brain lesions. The diagnosis can be made on the basis of the combination of a typical clinical profile and characteristic radiologic findings. We experienced a first case of acute necrotizing encephalopathy in a 9 month old boy in Korea. We report this case with the brief review of related literatures.

Key Words: Acute necrotizing encephalopathy, Thalamus, Brainstem tegmentum